Tisenc Accre 8 chemiluminescence analyzer, front three-quarter view
Tisenc Accre 8 chemiluminescence analyzer, side view
Accre 8 reaction chamber with six reagent cartridges loaded in the rack
Tisenc single-test chemiluminescence reagent cartridge

Tisenc Accre 8 Chemiluminescence Analyzer

A benchtop chemiluminescence (CLIA) analyzer that runs up to six progesterone samples at once, from 80 µL of serum or plasma, with results in about 23 minutes. Same detection method as the reference laboratory, on your own bench.

  • 6-channel random access, 36 tests per hour
  • Calibrator traceable to Roche Elecsys / cobas e411
  • Sealed single-test cartridges, no liquid path to maintain
  • 15.6″ touchscreen, built-in printer and QC charts

New to our range. Pricing and lead time on request.

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  • Analyzer only — progesterone reagent kits (36 or 60 tests, with or without controls) are ordered separately
  • Fully automated single-test chemiluminescence immunoassay (CLIA) on magnetic microparticles
  • 6 channels, random access — up to 36 tests per hour; progesterone in about 23 minutes
  • Sample of 80 µL serum or plasma per test (pipette at least 100 µL into the cartridge)
  • Progesterone calibrator traceable to Roche cobas e411 / Elecsys; measuring range 0.5–191 nmol/L (about 0.16–60 ng/mL)
  • 3-point calibration from the barcode sheet in each kit, valid 28 days; two-level QC with Levey–Jennings charts on the instrument
  • 15.6″ colour touchscreen, built-in thermal printer and reagent barcode scanner; USB, RS-232 and network port with LIS support
  • No liquid path inside — maintenance-free, with no analyzer consumables beyond cartridges and tips
  • Benchtop: 370 × 600 × 500 mm, 42 kg, mains powered; 24-hour standby with one-touch restart
  • Special order · pricing and lead time on request · training and technical support included

Accre 8 or Pro-DX?

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Accre 8
Price on request
 Pro-DX
$2,199.99
Method Chemiluminescence (CLIA) Fluorescence immunoassay
Samples per run Up to 6, random access 1 (Quick Test mode staggers several)
Time to result About 23 minutes About 15 minutes
Sample 80 µL serum or plasma 75 µL whole blood, serum or plasma
Calibration 3-point, per lot or every 28 days; controls in the kit None — lot data on the kit ID chip
Screen and output 15.6″ touchscreen, built-in printer, USB / RS-232 / network 8″ touchscreen, Wi-Fi
Footprint and power Benchtop, 42 kg, mains Portable, 3.3 kg, battery for 800 tests
Best for Repro clinics and large kennels timing many cycles at once A single kennel timing a few litters a year, or testing on the road
The two analyzers report progesterone on different scales. Time from the chart supplied for the instrument you are using; do not carry a threshold from one to the other.

Downloads

Both documents are the manufacturer’s originals (Shenzhen Tisenc Medical Devices, a Wondfo company). The brochure lists the full clinical test menu the platform supports; on this site the Accre 8 is supplied with the progesterone assay for canine reproduction.

Analyzer

Method Enzyme-catalysed chemiluminescence immunoassay (CLIA); alkaline phosphatase label, APS-5 substrate, nano-magnetic particle separation, photomultiplier detection
Channels 1 module, 6 channels, random access
Throughput 36 tests per hour; first result in 10–25 minutes depending on assay
Sample types Whole blood, serum or plasma (assay-specific — progesterone uses serum or plasma)
Screen 15.6″ colour touchscreen; Linux system
Printer Built-in thermal printer; external printer optional
Barcode Built-in reagent barcode scanner; optional handheld scanner for sample IDs
Connectivity USB, RS-232, network port; LIS / HIS connection
Data 100,000 results stored; test and calibration results saved automatically; built-in Levey–Jennings QC charts
Internal design No liquid path — integrated sampling, wash, reaction and incubation modules; maintenance-free
Power Mains; 24-hour standby with one-touch restart
Dimensions 370 × 600 × 500 mm (14.6 × 23.6 × 19.7 in)
Weight 42 kg (93 lb)
STAT No (available on Accre 90 / 160)
Manufacturer: Shenzhen Tisenc Medical Devices Co., Ltd., a Wondfo company. The Accre 6, 8, 90 and 160 all run the same single-test cartridge.

Progesterone (CLIA) assay

Principle Competitive immunoassay with enzyme-catalysed chemiluminescence detection
Measuring range 0.5–191 nmol/L (about 0.16–60 ng/mL); limit of detection 0.5 nmol/L (CLSI EP17-A2)
Units Reported in nmol/L; nmol/L × 0.314 = ng/mL
Precision Within-lot CV under 10%; between-lot CV under 15% (CLSI EP05-A3)
Linearity Linear from 0.5 to 191 nmol/L, r > 0.99 (CLSI EP06-A)
Traceability Kit calibrator traced to Roche cobas e411 / Elecsys progesterone
Sample 80 µL serum or plasma (sodium heparin, EDTA-K2 or EDTA-K3); pipette at least 100 µL into the cartridge
Sample stability 8 hours at 15–30 °C, 5 days at 2–8 °C, 6 months frozen at −20 °C (one freeze–thaw)
Time to result Approximately 23 minutes
Calibration 3-point, from the calibrator barcode sheet in the kit; required for each new lot, after 4 weeks on the same lot, or when QC fails
Dilution Manual 1:5 in negative serum or plasma for samples above 191 nmol/L; no automatic dilution
Interference None significant up to haemoglobin 500 mg/dL, bilirubin 20 mg/dL, triglyceride 1,500 mg/dL, total protein 10 g/dL, rheumatoid factor 1,000 IU/mL (CLSI EP07-A3)
Kit storage 2–8 °C, upright, in the dark; 18-month shelf life; cartridges on board up to 2 hours; opened calibrators 30 days at 2–8 °C

Reagent kit configurations

REF Cartridges Calibrators Controls
W44A 60 tests CAL1–3, 1 mL each QC1 and QC2, 1 mL each
W44C 36 tests CAL1–3, 1 mL each QC1 and QC2, 1 mL each
W52A 60 tests CAL1–3, 1 mL each —
W52C 36 tests CAL1–3, 1 mL each —
Every kit also contains the instructions for use, a reagent registration card, a calibrator barcode sheet and disposable tips. Kits with controls add a quality control sheet with lot target values.
The assay package insert (Tisenc, ver 5.0, 2022) is written for serum and plasma and its printed reference intervals are not canine values. Progesterone thresholds are specific to the assay that produced them; values from a different analyzer or laboratory are not directly interchangeable — see why your analyzer’s chart doesn’t match the textbook.
Every reagent the assay needs is already sealed inside the single-test cartridge, so a run is four steps: pipette, load, touch start, print. Tisenc quotes 30 minutes to learn the routine.
  1. Register the assay and the lot
    The first time you use progesterone on the analyzer, enter the registration code from the reagent kit. Repeat for every new lot using the Reagent Registration Card in the box — calibration, QC and sample tests are only available once the lot is registered.
  2. Calibrate when required
    Run the three calibrators, reading their values from the Calibrator Barcode Sheet. Calibration is needed for each new lot, after four weeks on the same lot, when a control falls out of range, or after service. The curve is stored on the analyzer and valid for 28 days.
  3. Prepare the sample
    Spin the blood down and use serum or plasma (heparin or EDTA). Let cartridges, samples and controls reach room temperature. Mix on a vortex if needed and make sure there are no bubbles — pipette at least 100 µL into the sample well of each cartridge (the assay draws 80 µL).
  4. Load the rack
    Insert one cartridge per sample into the reagent rack (one to six), place the rack in the reaction chamber and add a fresh tip for each position. The built-in scanner reads every cartridge barcode automatically.
  5. Touch START
    Enter the sample IDs from the on-screen keyboard or a barcode scanner and start the run. Incubation, magnetic separation, three washes, substrate and reading all happen inside the instrument; progesterone completes in about 23 minutes.
  6. Read, print, dispose
    Results appear on screen in nmol/L (multiply by 0.314 for ng/mL) and print on the built-in thermal printer. Remove the rack and discard used cartridges and tips as clinical waste. The analyzer stores 100,000 results and keeps Levey–Jennings charts for your controls.

Good habits that protect the number

  • Keep kits at 2–8 °C, upright and out of sunlight; never freeze cartridges, and finish testing within 2 hours of a cartridge going on board
  • Do not mix cartridges, calibrators or controls between lots, and do not turn a cartridge upside down
  • Severely haemolysed samples are not recommended; centrifuge again if you can see fibrin or a lipid layer
  • Samples above 191 nmol/L (60 ng/mL) can be diluted 1:5 by hand and multiplied back — the analyzer does not dilute automatically
  • Wear powderless gloves; glove powder is a known cause of false results in enzyme immunoassays
The package insert is the authority
Every kit ships with a package insert giving the exact volumes, timings and handling steps for that lot, and the Instrument User Manual covers the analyzer itself. Where either differs from this summary, follow the document. Training and technical support are included with your purchase if anything is unclear.

Download the Accre 8 User Manual (PDF) →

The Tisenc Accre 8 brings laboratory chemiluminescence to the breeding kennel and reproduction clinic. It is a fully automated, single-test CLIA analyzer: you pipette the sample into a sealed reagent cartridge, load up to six cartridges at a time, and the instrument does the incubation, magnetic separation, washing and reading on its own. Progesterone comes back in about 23 minutes on a calibrator traceable to the Roche Elecsys system — the same method family most reference laboratories use.

Why breeders and repro vets choose it

Six dogs, one run
Six independent channels with random access — start a new sample while others are still running. Up to 36 results an hour on a busy morning.
Reference-lab chemistry
Enzyme-catalysed chemiluminescence on paramagnetic particles, read by a photomultiplier. The progesterone calibrator is traced to Roche cobas e411 / Elecsys.
Load-and-go cartridges
Every reagent is pre-dispensed and foil-sealed in a single-test strip. A built-in scanner reads the lot barcode, so there is nothing to mix and nothing to program.
No liquid path to maintain
No tubing, pumps or wash bottles inside — only mechanical modules. No daily maintenance routine and no analyzer consumables beyond the cartridge and tip.
15.6″ touchscreen + printer
Every step is done on the large colour touchscreen. Results print on the built-in thermal printer, or export over USB, RS-232 or the network port.
Quality control built in
Two-level controls and calibrators ship in the kit; the analyzer keeps Levey–Jennings QC charts and stores 100,000 results on board.
New to our range
The Accre 8 is a special-order instrument. Tell us how many cycles you time in a season and we will come back with pricing, lead time and the right reagent configuration.

Request a quote →

See the Accre range in action

Manufacturer overview of the Accre family. The Accre 8 shown here shares its single-test cartridge with the larger Accre 90 and 160.

Also consider

Testing one dog at a time?
The Pro-DX is our portable fluorescence analyzer: one sample, about 15 minutes, runs on a battery and needs no calibration step. It is the better fit for a single kennel timing a few litters a year.

See the Pro-DX →

Want everything on day one?
The Pro-DX start-up bundle adds a 10-test kit, centrifuge, vortex mixer, pipette and blood-draw supplies to the analyzer.

See the Pro-DX Bundle →

New to progesterone timing?

The instrument is only half the picture — knowing what the numbers mean is the other half. Our free, evidence-based guides cover timing the cycle, reading results and matching insemination method to the window. Explore the Progesterone Library →
The Accre 8 reports progesterone in nmol/L on a chemiluminescence scale (multiply by 0.314 for ng/mL). Progesterone thresholds belong to the assay that produced them — see how the common analyzers compare before carrying a number from one instrument to another.

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